I-Pramlintide Acetate CAS: 196078-30-5 Ukunikezwa kwezinto ezibonakalayo
Incazelo Yomkhiqizo
I-Pramlintide (i-Symlin) iwumuthi omusha omjova wesifo sikashukela (zombili uhlobo 1 no-2), othuthukiswe i-Amylin Pharmaceuticals (manje eyinkampani ephethwe ngokuphelele ye-AstraZeneca ) IPramlintide ithengiswa njengosawoti we-acetate.
I-Pramlintide iyi-analogue ye-amylin, ihomoni encane ye-peptide ekhishwa egazini ngama-β-cell we-pancreas kanye ne-insulin, ngemva kokudla.Njenge-insulin, i-amylin ayikho ngokuphelele kubantu abanesifo sikashukela soHlobo I.
Ukwehla kwe-hemoglobin ye-glycated kanye nokuncipha kwesisindo kukhonjisiwe ezigulini ezilashwa nge-insulin ezinesifo sikashukela sohlobo 2 ezithatha i-pramlintide njengokwelashwa okungeziwe.
Ngokwandisa i-amylin engokwemvelo, izinsiza ze-pramlintide ekumunceni kwamangqamuzana kanye nokulawula ushukela wegazi ngokunciphisa ukuphuma kwesisu, ikhuthaze ukusutha ngama-hypothalamic receptors (ama-receptors ahlukene kune-GLP-1), futhi ivimbele ukukhishwa okungafanele kwe-glucagon, ihomoni elinamandla eliphikisana nemiphumela. I-insulin ne-amylin.I-Pramlintide nayo inemiphumela ekukhuliseni umkhawulo wokuphendula we-insulin wesigaba sokuqala ngemuva kokudla.
Iphrofayela Yenkampani
I-SaiWanTe (Shanghai) New Material Technology Co., Ltd yinkampani yokuhweba yangaphandle, egxile ekuthuthukiseni nasekukhiqizeni i-Organic intermediate.Inemboni yayo, ezithengela yona ukuncintisana emakethe.Iminyaka eminingi, inkampani yethu izuze ukwesekwa nokuthenjwa kwamakhasimende amaningi ngoba ihlale ilwela ukwenza okuthengiswayo kwekhwalithi ephezulu ngentengo evumayo.Izibophezela ukwanelisa wonke amaklayenti, ngokubuyisela, ikhasimende lethu libonisa ukuzethemba okukhulu nenhlonipho ngenkampani yethu.Naphezu kwamakhasimende amaningi athembekile awinile kule minyaka, i-Weitai igcina isizotha ngaso sonke isikhathi futhi ilwela ukuzithuthukisa kuzo zonke izici.Sibheke ngabomvu ukubambisana nawe nokuba nobudlelwano bokunqoba nawe.Sicela uqiniseke ukuthi sizokwanelisa.Vele ukhululeke ukuxhumana nami.
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