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umkhiqizo

Umkhiqizi Supply Cilengitide 98% powder emhlophe CAS NO.188968-51-6

I-Cilengitide CAS NO: 188968-51-6
I-Cilengitide iyi-peptide ye-cyclic pentapeptide eqhudelana ne-arginine-glycine-aspartate (RGD) peptide sequence.Ilawula ukubophezela kwe-integrin-ligand.I-Cilengitide ivimbela ngokukhetha nangempumelelo i-alpha v beta 3 beta kanye ne-alpha v 5 integrin ehlanganiswe namaprotheni e-matrix, njenge-Vitronectin, i-Fibronectin, i-Fibrinogen, i-vonWillebrandFactor, i-Osteopontin, namanye.I-10μMCingiChemicalbooktide ivimbela ngokuphelele ukunamathela kwe-BAE, BME kanye namaseli e-HUVE ku-Vitronectin ne-Fibronectin.I-Cilengitide isebenza nge-vitro kumaseli e-BAE enziwe ngaphambili nge-FGF-2(noma i-VEGF-A) ye-collagen enezinhlangothi ezintathu nejeli ye-fibrin yegazi ukuvimbela i-angiogenesis nge-IC50 ye-15 ne-8μM, kanye ne-4 kanye ne-3μM, ngokulandelanayo.I-Cilengitide ivimbela ukwanda kwamaseli, yenza i-endothelial cell apoptosis, futhi ibangele ukuhlukaniswa kweseli endothelial eyandulela.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo Yomkhiqizo

Igama Lomkhiqizo I-Cilengitide
I-CAS 188968-51-6
ifomula yamangqamuzana I-C27H40N8O7
isisindo samangqamuzana 588.66
ukuminyana 1.41±0.1 g/cm3(Kubikezelwe)
ukuncibilika ≥29.43 mg/mL ku-DMSO;≥22.56 mg/mL ku-H2O
I-acidity coefficient (pKa) 4.01±0.10(Okubikezelwe)
misa (1)
misa (1)
misa (2)

Iphrofayela Yenkampani

I-SaiWanTe (Shanghai) New Material Technology Co., Ltd.iyi-R & D yochwepheshe kanye nokukhiqizwa kwezinhlayiya zepulasitiki, intambo, izithasiselo zokudla, inkampani yohwebo lwangaphandle.Izimonyo, njll., zinamafekthri azo, Ngakho-ke, siye saqashelwa ngobuqotho amakhasimende amaningi.Naphezu kweziningi kangaka esizizuzile, sisazama ukwenza impumelelo kule mboni.Inhloso yethu ukukhiqiza imikhiqizo engcono kakhulu, enesevisi yobungcweti nesimo sengqondo sokwenza wonke amakhasimende aneliseke.Sibheke ngabomvu ukusebenzisana nawe ukwakha ubudlelwano bokunqoba nawe.Sicela uqiniseke ukuthi sizokunikeza ukwaneliseka.

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